Author(s): Wallingford JB
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Abstract Planar cell polarity signaling governs a wide array of polarized cell behaviors in animals. Recent reports now show that PCP signaling is essential for the directional beating of motile cilia. Interestingly, PCP signaling acts in a variety of ciliated cell types that use motile cilia to generate directional fluid flow in very different ways. This review will synthesize these recent papers and place them in context with previous studies of PCP signaling in polarized cellular morphogenesis and collective cell movement. Copyright © 2010 Elsevier Ltd. All rights reserved.
This article was published in Curr Opin Cell Biol
and referenced in Journal of Alzheimers Disease & Parkinsonism