alexa Plasma total protein measurement for prediction of disease and mortality in calves.

Author(s): Naylor JM, Kronfeld DS, BechNielsen S, Bartholomew RC

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Abstract Plasma concentration of total protein (TP) was measured by refractometer in 76 calves, 1 to 8 days of age, on 3 farms. Three calves died before weaning at 5 weeks; all had plasma TP less than 6 g/dl. The frequency of disease before weaning was 17/29 (59\%) in calves that had plasma TP of less than or equal to 6 g/dl, and this was significantly (P less than 0.001) less than the disease frequency of 9/47 (19\%) in those with higher values of plasma TP. For 9 calves, plasma TP content was 4.72 +/- 0.22 (mean +/- SD) before ingestion of colostrum. The increment of plasma TP after colostrum feeding was 2.03 +/- 0.61 mg/dl (P less than 0.001). Plasma TP was as useful as serum zinc sulfate turbidity test results or total immunoglobins (as measured by radial immunodiffusion) in predicting disease susceptibility during the first 5 weeks of life, based on determinations made in 32 calves during the first 8 days of life. It was concluded that determination of plasma TP is the most convenient method of evaluating the immune status of calves under field conditions.
This article was published in J Am Vet Med Assoc and referenced in

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