alexa Pooled analysis of two case-control studies on use of cellular and cordless telephones and the risk for malignant brain tumours diagnosed in 1997-2003.
Chemistry

Chemistry

Journal of Physical Chemistry & Biophysics

Author(s): Hardell L, Carlberg M, Hansson Mild K

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Abstract OBJECTIVES: To study the use of cellular and cordless telephones and the risk for malignant brain tumours. METHODS: Two case-control studies on malignant brain tumours diagnosed during 1997-2003 included answers from 905 (90\%) cases and 2,162 (89\%) controls aged 20-80 years. We present pooled analysis of the results in the two studies. RESULTS: Cumulative lifetime use for >2,000 h yielded for analogue cellular phones odds ratio (OR)=5.9, 95\% confidence interval (CI)=2.5-14, digital cellular phones OR=3.7, 95\% CI=1.7-7.7, and for cordless phones OR=2.3, 95\% CI=1.5-3.6. Ipsilateral exposure increased the risk for malignant brain tumours; analogue OR=2.1, 95\% CI=1.5-2.9, digital OR=1.8, 95\% CI=1.4-2.4, and cordless OR=1.7, 95\% CI=1.3-2.2. For high-grade astrocytoma using >10 year latency period analogue phones yielded OR=2.7, 95\% CI=1.8-4.2, digital phones OR=3.8, 95\% CI=1.8-8.1, and cordless phones OR=2.2, 95\% CI=1.3-3.9. In the multivariate analysis all phone types increased the risk. Regarding digital phones OR=3.7, 95\% CI=1.5-9.1 and cordless phones OR=2.1, 95\% CI=0.97-4.6 were calculated for malignant brain tumours for subjects with first use use <20 years of age, higher than in older persons. CONCLUSION: Increased risk was obtained for both cellular and cordless phones, highest in the group with >10 years latency period. This article was published in Int Arch Occup Environ Health and referenced in Journal of Physical Chemistry & Biophysics

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