alexa Possible mechanism of hepatoprotective activity of Azadirachta indica leaf extract: part II.
Chemical Engineering

Chemical Engineering

Journal of Chromatography & Separation Techniques

Author(s): Chattopadhyay RR

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Abstract Hepatoprotective activity of Azadirachta indica leaf extract against paracetamol induced hepatic damage in rats has already been reported. In the present investigation effects of Azadirachta indica leaf extract on blood and liver glutathione, Na+K(+)-ATPase activity and thiobarbutiric acid reactive substances against paracetamol induced hepatic damage in rats have been studied with a view to elucidate possible mechanism behind its hepatoprotective action. It was interesting to observe that Azadirachta indica leaf extract has reversal effects on the levels of above mentioned parameters in paracetamol hepatotoxicity. Possible mechanism behind the results are discussed.
This article was published in J Ethnopharmacol and referenced in Journal of Chromatography & Separation Techniques

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