alexa Preconception care of diabetes. Glycemic control prevents congenital anomalies.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Kitzmiller JL, Gavin LA, Gin GD, JovanovicPeterson L, Main EK, , Kitzmiller JL, Gavin LA, Gin GD, JovanovicPeterson L, Main EK,

Abstract Share this page

Abstract To test the value of intensive management of diabetes before and during early pregnancy, 84 women recruited prior to conception were compared with 110 women who were already pregnant referred at 6 to 30 weeks' gestation. All underwent daily measurement of fasting and postprandial capillary blood glucose levels. Mean blood glucose levels during embryogenesis and organogenesis were within 3.3 to 7.8 mmol/L in 50\% of preconception subjects and exceeded 10 mmol/L in 6.5\%. One major congenital anomaly occurred in 84 infants (1.2\%) of women treated before conception compared with 12 anomalies in 110 infants (10.9\%) of mothers in the postconception group. Transient symptomatic hypoglycemia occurred during embryogenesis in 60\% of women in the preconception group, with a median frequency of 2.7 episodes per week, but was not associated with excess malformations. We conclude that education and intensive management for glycemic control of diabetic women before and during early pregnancy will prevent excess rates of congenital anomalies in their infants.
This article was published in JAMA and referenced in Journal of AIDS & Clinical Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords