alexa Predisposing factors, clinical and microbiological aspects of bacterial keratitis: a clinical study.


Journal of Clinical & Experimental Ophthalmology

Author(s): Cruciani F, Cuozzo G, Di Pillo S, Cavallaro M

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Abstract PURPOSE: To identify predisposing factors and to evaluate clinical and microbiological characteristics of bacterial keratitis. MATERIALS AND METHODS: A retrospective analysis was performed on the charts of patients hospitalized for microbial keratitis and treated at the Department of Ophthalmology of the Policlinico Umberto I Hospital, Rome, Italy. The study was performed during a 42-month period. Risk factors, clinical and microbiological data were collected. RESULTS: A total of 65 patients with bacterial keratitis were documented. Contact lens wear was the most common risk factor (46.1\%). Trauma or a history of keratopathy was found in 18.5\% and 15.4\% of cases, respectively. An organism was identified in 62\% of cases. 74\% of all positive cultures involved gram negative bacteria. The most frequently cultured organism was Pseudomonas aeruginosa alone (72.2\%) or in combination with other microorganisms (16.7\%). Fifty-eight per cent of patients had visual acuity better than the level at admission, and 12\% had very poor visual outcome. CONCLUSIONS: Contact lens wear is the most important risk factor. The role of initial therapy for microbial keratitis remains important.
This article was published in Clin Ter and referenced in Journal of Clinical & Experimental Ophthalmology

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