alexa Prevalence and characteristics of uveitis in the spondyloarthropathies: a systematic literature review.
Neurology

Neurology

Journal of Spine

Author(s): Zeboulon N, Dougados M, Gossec L

Abstract Share this page

Abstract BACKGROUND: Uveitis is reported to be the most common extra-articular manifestation in spondyloarthritis (SpA); however, its prevalence and characteristics are not well established. OBJECTIVE: To perform a systematic literature review in order to examine these topics. METHODS: A systematic literature analysis was conducted in the Medline database up to October 2006 and in the abstracts of rheumatology scientific meetings for the years 2004, 2005 and 2006. A hand search of references was also performed. Articles were analysed if they reported the prevalence or characteristics of uveitis in SpA. Data abstraction was standardised. Statistical analysis was mainly descriptive. RESULTS: Among the 957 articles selected by the search, 126 articles (29,877 patients) allowed a calculation of the prevalence of uveitis in SpA; 36 articles (1989 patients) described its characteristics. The mean (SD) prevalence of uveitis was 32.7 (0.5)\%; it varied with the type of SpA--for example, 33.2 (0.8)\% for ankylosing spondylitis versus 25.1 (2.3)\% for psoriatic arthritis. This prevalence increased with mean disease duration and was higher in HLA-B27-positive patients with an odds ratio of 4.2. Uveitis was acute in 88.7 (2.5)\%, anterior in 90.5 (2.0)\%, unilateral in 87.3 (2.8)\%. Recurrence occurred in 50.6 (2.6)\% and a reduction of visual acuity was observed in 8.3 (3.8)\%. CONCLUSION: The prevalence of uveitis varies with disease duration and according to the type of SpA. Reduction of visual acuity is not exceptional. Because of recent promising data about the effects of anti-tumour necrosis factor therapy on uveitis flares in SpA, it was important to determine this baseline prevalence. This article was published in Ann Rheum Dis and referenced in Journal of Spine

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • 18th Global Neurologists Annual Meeting on Neurology and Neurosurgery
    Nov 13-15, 2017, Athens, Greece
  • 2nd International Conference on Pediatric Neurology  
    August 31-September 01, 2017 Prague, Czech Republic
  • 12th Global Neurologists Annual Meeting on Neurology and Neurosurgery
    November 16-18, 2017 Lisbon, Portugal

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords