alexa Prevalence and correlates of willingness to participate in a rectal microbicide trial among men who have sex with men in Bangkok.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Thienkrua W, Todd CS, Chaikummao S, Sukwicha W, Yafant S, , Thienkrua W, Todd CS, Chaikummao S, Sukwicha W, Yafant S,

Abstract Share this page

Abstract Rectal microbicides (RMs) hold promise as a HIV prevention method to reduce transmission among men who have sex with men (MSM). To assess RM trial feasibility in Bangkok, we measured prevalence and correlates of willingness to participate among Thai MSM observational cohort participants. Between April 2006 and December 2010, 1744 MSM enrolled in the Bangkok MSM Cohort Study; at 12 months, RM trial participation willingness was measured. We evaluated correlates of RM trial participation willingness using logistic regression analysis. Participants completing the 12-month visit (81.4\%, n = 1419) had a mean age of 27.3 years (SD = 6.1), and 65.5\% and 86.1\% reported having a steady partner or anal intercourse (AI) in the past four months, respectively. Most (79.1\%, n = 1123) participants reported willingness to participate in an RM trial, which, in multivariable analysis, was independently associated with insertive only (adjusted odds ratio [AOR] = 3.25, 95\% CI: 1.82-5.81) or receptive/versatile role AI (AOR = 3.07, 95\% CI: 1.88-5.01), and being paid for sex (AOR = 12.15, 95\% CI: 1.67-88.21) in the past four months, and believing that people with AIDS look sick (AOR = 1.92, 95\% CI: 1.23-2.98). Of hypothetical RM trial features to increase enrollment likelihood, the most (91.1\%) compelling was that the study be approved by the Thai ethics committee, followed by the study site offering evening hours (88.9\%). Reasons not to participate were not wanting a rectal examination (29.5\%) or fluid collected from the penis or anus (24.6\%) and not wanting the placebo (23.0\%). RM trial participation willingness was high, particularly for those with greater HIV acquisition risk, within this Thai MSM cohort, suggesting feasibility of an RM trial. Addressing potential barriers to trial entry may be useful in educational materials to optimize recruitment. This article was published in AIDS Care and referenced in Journal of AIDS & Clinical Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords