alexa Prevalence of bronchial hyperresponsiveness among HIV-infected men.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Poirier CD, Inhaber N, Lalonde RG, Ernst P, Poirier CD, Inhaber N, Lalonde RG, Ernst P

Abstract Share this page

Abstract HIV infection is associated with immune dysregulation primarily affecting T-cell function, whereas asthma is related to excessive T-cell activity. We compared the prevalence of asthma and related conditions among adult seropositive men with the prevalence among men of similar age drawn from the general population. Seropositive men had a significantly more frequent occurrence of wheezing (54.4 versus 21.2\%), bronchial hyperresponsiveness (BHR) to methacholine (26.2 versus 14.4\%), and an elevated total serum IgE (37.8 versus 25.7\%). Differences in BHR were significant only among smokers. Among the seropositive men, FEV(1)/FVC and an elevated IgE were the principal determinants of BHR. Our results suggest that the frequency of asthma may be underestimated in HIV disease. Furthermore, the frequent occurrence of BHR in HIV-infected men who smoke (30.1\%) suggests this group may be especially susceptible to the adverse effects of cigarette smoke. This article was published in Am J Respir Crit Care Med and referenced in Journal of AIDS & Clinical Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords