Author(s): Jonasson F, Damji KF, Arnarsson A, Sverrisson T, Wang L,
Abstract Share this page
Abstract PURPOSE: To establish the age- and sex-specific prevalence of open-angle glaucoma (OAG) subsuming pseudoexfoliation (PEX) in the city of Reykjavik. METHODS: Participants 50 years of age and older who were part of the Reykjavik Eye Study and classified as having glaucoma were divided into three categories:Category 1: two or more of the following based on optic nerve stereophotograph reading: vertical cup to disc ratio (VCDR) 97.5th percentile (>0.7), focal glaucomatous disc change, C/D asymmetry of 97.5th percentile difference between eyes (>0.2) as well as glaucomatous visual field defect (GVFD). Category 2: 99.5th percentile of VCDR (>0.8) and 99.5\% percentile difference between eyes (>/=0.3), without a GVFD. Category 3: VA<3/60 and IOP>99.5th percentile or VA <3/60 and evidence of filtering surgery. For a glaucoma suspect, one of the following was present: VCDR>99.5th percentile (>0.8), focal glaucomatous disc change, C/D asymmetry of 99.5th percentile (> or =0.3), GVFD only, IOP> or =23 mmHg (97.5 percentile). PEX was diagnosed by the presence of a central shield and/or a peripheral band on the anterior lens capsule. RESULTS: Of 42 persons (22 males and 20 females) with OAG, 13 (31.0\%) had PEX. The minimum prevalence of OAG was 4.0\% (42/1045) (95\% CI 2.8-5.2) for those 50 years and older and 10.3\% (95\% CI 8.5-12.2) for PEX. The prevalence of OAG increases with age (OR=1.10/year, 95\% CI 1.07-1.13, P=0.000) and the same applies for the prevalence of PEX, OR=1.10 (95\% CI 1.07-1.12, P=0.000). CONCLUSION: There is a 10\% annual increase for both OAG and PEX in persons 50 years and older.
This article was published in Eye (Lond)
and referenced in Journal of Clinical & Experimental Ophthalmology