Author(s): Beach KW, Brunzell JD, Strandness DE Jr
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Abstract Noninvasive methods were used to determine the prevalence and severity of arteriosclerosis obliterans associated with diabetes in 674 subjects including 153 recruited as controls. A resting ankle systolic blood pressure that was less than 90\% of the arm pressure indicated severe arteriosclerosis obliterans. Of the 71 subjects with severe disease, 64 (90\%) had a history of smoking, which is significantly greater than the 60\% overall smoking rate (p less than 0.001). In non-insulin-dependent diabetic smokers, the diet-treated subjects had 2.5 times the prevalence of severe arteriosclerosis obliterans as those treated with insulin (p = 0.01); the sulfonylurea-treated subjects had twice the prevalence of severe disease as those treated with insulin (p = 0.015).
This article was published in Arteriosclerosis
and referenced in Journal of Clinical & Experimental Cardiology