alexa [Prevention and management of lung infections with thymosin alpha1 in critical patients with tracheotomy].
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Clinical & Experimental Pharmacology

Author(s): Huang DP, Yang M, Peng WP, Chen XS, Chen ZQ

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Abstract OBJECTIVE: To evaluate the preventive and therapeutic effect of thymosin alpha(1) on lung infections in critical patients with tracheotomy. METHODS: Forty-two patients were randomly divided into treatment group and control group to receive daily subcutaneous thymosin injection at 11.6 mg and saline of 2 ml for 7 days, respectively. RESULTS: Compared with the control group, the infection rate, white blood cell count, C-reactive protein, tumor necrosis factor-alpha and interleukiu-6 were significantly lower in the treatment group. CONCLUSION: Thymosin alpha(1) can be effective for prevention and treatment of lung infections in critical patients with tracheotomy and may improve the patients' immunity and prognosis.
This article was published in Nan Fang Yi Ke Da Xue Xue Bao and referenced in Journal of Clinical & Experimental Pharmacology

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