alexa Primary biliary cirrhosis. A patient with adverse reactions to tiopronin and autoimmune hemolytic anemia with reticulocytopenia.
Medicine

Medicine

Internal Medicine: Open Access

Author(s): Shichiri M, Koyama W, Tozuka S, Sakamoto S, Kanayama M

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Abstract A 32-year-old woman with asymptomatic primary biliary cirrhosis had autoimmune hemolytic anemia associated with reticulocytopenia and thrombocytopenia despite an intensely erythroid bone marrow. Her anemia was successfully treated with oral prednisolone and intravenous pulse methylprednisolone, with a rapid response of reticulocytosis and sustained erythrocytosis. Tiopronin therapy was later initiated and resulted in fever, rash, exacerbation of the liver disease, and positive direct and indirect antiglobulin tests.
This article was published in Arch Intern Med and referenced in Internal Medicine: Open Access

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