alexa Primary malignant melanoma of the vagina with repeated local recurrences and brain metastasis.
Reproductive Medicine

Reproductive Medicine

Gynecology & Obstetrics

Author(s): Lin LT, Liu CB, Chen SN, Chiang AJ, Liou WS

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Malignant melanoma of the vagina, a very rare malignancy, has a notoriously aggressive behavior associated with a high risk of local recurrence and distant metastasis. At present, there are various treatment options for this disease but no standard guideline. We describe a case of a 54-year-old woman with a locally advanced melanoma of the vagina, who underwent radical surgery, biochemotherapy with interferon-α-2b, chemotherapy, radiotherapy, and repeat excision of local recurrent lesions and brain metastasis. In conclusion, malignant melanoma of the vagina has a high risk for local recurrence. Repeated local excision followed by biochemotherapy is a tolerable treatment.

This article was published in J Chin Med Assoc. and referenced in Gynecology & Obstetrics

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