alexa Primary melanocytic neoplasms of the central nervous system.


Journal of Pigmentary Disorders

Author(s): Liubinas SV, Maartens N, Drummond KJ

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Abstract Primary melanocytic neoplasms of the central nervous system (CNS) are rare lesions arising from melanocytes of the leptomeninges. They include diffuse leptomeningeal melanocytosis or melanomatosis, melanocytoma and primary malignant melanoma. We have reviewed the English literature regarding these lesions, which consists of case reports and a small number of larger case series. The presenting features, radiological, surgical and histological findings are reviewed, as are current management options and prognosis. We also present illustrative case reports of diffuse leptomeningeal melanocytosis and primary melanoma of the CNS. Copyright 2010 Elsevier Ltd. All rights reserved. This article was published in J Clin Neurosci and referenced in Journal of Pigmentary Disorders

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