alexa Production of sophorolipids with eicosapentaenoic acid and docosahexaenoic acid from Wickerhamielladomercqiae var. sophorolipid using fish oil as a hydrophobic carbon source


Research & Reviews: Journal of Microbiology and Biotechnology

Author(s): Li H

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Sophorolipids (SLs) were synthesized by Wickerhamiella domercqiae var. sophorolipid CGMCC 1576 grown on fish oil and glucose. They were purified using preparative HPLC and their structures were identified by MS/MS. The yields of total and lactonic SLs were 47 and 19 g l−1 in shake-flasks when fish oil 4 % (v/v) was used with glucose in the medium. The composition of SL mixture contained more than 20 SL molecules. Several unconventional SL molecules with eicosapentaenoic acid (EPA) or docosahexaenoic acid (DHA) including zero-, mono- and di-acetylated acidic SLs with EPA and a di-acetylated acidic SL with DHA were obtained. Two unconventional lactonic SL molecules, non-acetylated lactonic SL with 22:3 and non-acetylated lactonic SL with 20:0, were also obtained.

This article was published in BiotechnolLett and referenced in Research & Reviews: Journal of Microbiology and Biotechnology

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