alexa Progesterone and estrogens in rat brain: modulation of GABA (gamma-aminobutyric acid) receptor activity.


Journal of Depression and Anxiety

Author(s): Maggi A, Perez J

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Abstract Our data indicate that estrogens and progesterone can regulate the number of GABA receptors (as detected by [3H]muscimol binding assay) in rat brain. Both hormones act in selected areas. The extent of the effect (up to 160\% increase) and the number of areas responsive suggest that sex hormones may play a very important role in the regulation of the functions of GABAergic transmission in the central nervous system.
This article was published in Eur J Pharmacol and referenced in Journal of Depression and Anxiety

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