alexa Prophylactic intracameral cefuroxime. Efficacy in preventing endophthalmitis after cataract surgery.


Clinical Microbiology: Open Access

Author(s): Montan PG, Wejde G, Koranyi G, Rylander M

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Abstract PURPOSE: To evaluate the efficacy of prophylactic intracameral cefuroxime in preventing endophthalmitis in cataract surgery. SETTING: Department of Ophthalmology, St. Eriks Hospital, Stockholm, Sweden. METHODS: In a noncontrolled retrospective observational study, all cases of recorded postoperative endophthalmitis were related to the total number of uncombined cataract procedures from January 1996 to December 2000. RESULTS: Twenty cases of postoperative endophthalmitis occurred in 32180 procedures, yielding an overall rate of 0.06\%. Cefuroxime-resistant organisms accounted for 12 of 13 culture-positive cases, and enterococci were the most common etiology. CONCLUSIONS: Intracameral cefuroxime 1 mg appeared to effectively inhibit sensitive bacterial strains and was associated with a low frequency of postoperative endophthalmitis. The causative organisms of future incidents of postoperative endophthalmitis will determine whether the present protocol must be reappraised.
This article was published in J Cataract Refract Surg and referenced in Clinical Microbiology: Open Access

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