alexa Prophylactic use of mitomycin-C in the management of a buttonholed LASIK flap.


Journal of Clinical & Experimental Ophthalmology

Author(s): Lane HA, Majmudar PA

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We report a case in which prophylactic mitomycin-C (MMC) was used to prevent haze and scarring after photorefractive keratectomy (PRK) in an eye with a previous laser in situ keratomileusis flap buttonhole. During the patient's primary procedure, a 3.5 mm central buttonhole was created during the microkeratome pass. The flap was repositioned without laser application. Follow-up examinations revealed a moderate central buttonhole scar. Twelve months later, the patient had PRK with adjunctive MMC 0.02% application in the eye. At the 1-year examination, the uncorrected visual acuity was 20/20 and the cornea was clear with no evidence of scarring or haze.

This article was published in J Cataract Refract Surg. and referenced in Journal of Clinical & Experimental Ophthalmology

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