alexa Protective effects of L-arabinose in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats
Nutrition

Nutrition

Research & Reviews: Journal of Food and Dairy Technology

Author(s): Xiaoling Lu, Hao L, Min Sun, Kai Li, Lingmin Shen, Tao Wu

Abstract Share this page

Background: L-Arabinose is a non-caloric sugar, which could affect glucose and lipid metabolism andsuppress obesity. However, few reports have described the effect of L-arabinose in metabolic syndrome, acombination of medical disorders that increase the risk of diabetes and cardiovascular disease.Objective: This study was conducted to explore the effects of L-arabinose in rats with metabolic syndromeinduced by a high-carbohydrate, high-fat (HCHF) diet.Methods: After the rat model for metabolic syndrome was successfully established, L-arabinose wasadministrated by oral gavage for 6 weeks. The biochemical index and histological analysis were measured, andthe expression levels of genes related to fatty acid metabolism were analyzed using real-time PCR.Results: Following treatment with L-arabinose, metabolic syndrome rats had an obvious reduction in bodyweight, systolic blood pressure, diastolic blood pressure, fasting blood glucose, triglycerides, total cholesterol,serum insulin, TNF-a, and leptin. Further study showed that treatment with L-arabinose significantlyincreased the expression of mRNA for hepatic CPT-1a and PDK4, but the expression of mRNA for hepaticACCa was reduced.Conclusions: This work suggests that L-arabinose could lower body weight, Lee’s index, and visceral indexand improve dyslipidemia, insulin resistance, inflammation, and viscera function, which indicate that it mightbe a promising candidate for therapies combating metabolic syndrome.

  • To read the full article Visit
  • Open Access
This article was published in Food Nutr Res and referenced in Research & Reviews: Journal of Food and Dairy Technology

Relevant Speaker PPTs

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version