alexa Protein identification using 2D-LC-MS MS.
Chemical Engineering

Chemical Engineering

Journal of Chromatography & Separation Techniques

Author(s): Delahunty C, Yates JR rd

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Abstract Multidimensional liquid chromatography techniques have been coupled to tandem mass spectrometry to provide a robust method to identify proteins in complex mixtures. Data acquisition is interfaced directly with search algorithms for identification through cross-correlation with databases. This review describes the most recent advances in methodologies for protein identification by mass spectrometry and describes the limitations of the application of the technologies. This article was published in Methods and referenced in Journal of Chromatography & Separation Techniques

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