Author(s): Di Meglio P, Villanova F, Nestle FO, Di Meglio P, Villanova F, Nestle FO
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Abstract Psoriasis is a common chronic inflammatory skin disease with a spectrum of clinical phenotypes and results from the interplay of genetic, environmental, and immunological factors. Four decades of clinical and basic research on psoriasis have elucidated many of the pathogenic mechanisms underlying disease and paved the way to effective targeted therapies. Here, we review this progress and identify future directions of study that are supported by a more integrative research approach and aim at further improving the patients' life. Copyright © 2014 Cold Spring Harbor Laboratory Press; all rights reserved.
This article was published in Cold Spring Harb Perspect Med
and referenced in Journal of Neurology & Neurophysiology