alexa Psoriasis and metabolic syndrome.
Chemistry

Chemistry

Medicinal chemistry

Author(s): Malkic Salihbegovic E, Hadzigrahic N, Cickusic AJ

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Abstract INTRODUCTION: Psoriasis is a chronic skin ailment which can be connected with an increased occurrence of other illnesses, including the metabolic syndrome. EXAMINEES AND METHODS: A prospective study has been conducted which included 70 patients affected by psoriasis, both genders, older than 18 years. Average age being 47,14 (SD=±15,41) years, from that there were 36 men or 51,43 and 34 women or 48,57\%. The average duration of psoriasis was 15,52 (SD= ±12,54) years. For purposes of diagnosing the metabolic syndrome, the criteria of National Cholesterol Education Program Adult Treatment Panel III, (NCEP ATP III) were used. For purposes of detecting the severity and spread of psoriasis, Psoriasis Area and Severity Index (PASI) was used. RESULTS: The incidence of metabolic syndrome in patients with psoriasis was 38,57\%. Average values of PASI score were 16,65. The increase in values of PASI score and metabolic syndrome were statistically highly connected. (r=0,3, p=0,0001). CONCLUSION: Psoriasis is connected with metabolic syndrome, there is a positive correlation between the severity of psoriasis and frequency of metabolic syndrome.
This article was published in Med Arch and referenced in Medicinal chemistry

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