alexa Purification and studies of components of the haemostatic system by affinity chromatography.
Biomedical Sciences

Biomedical Sciences

Journal of Bioengineering & Biomedical Science

Author(s): Andersson LO

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Abstract The application of affinity chromatographic techniques for separations and studies on molecular interactions of the components of the blood coagulation system is reviewed. Most of the components have been purified using processes involving one or several affinity chromatographic steps. Many different kinds of affinity chromatography have been used, including inhibitor interaction chromatography, effector interaction chromatography, immunosorption, hydrophobic interaction chromatography, metal chelate chromatography and covalent chromatography. Affinity chromatographic techniques have also been used to study molecular interactions such as the fibrin polymerization process. One example of large-scale purification of a clinically used component is given.
This article was published in J Chromatogr and referenced in Journal of Bioengineering & Biomedical Science

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