alexa Pyogenic liver abscess: retrospective analysis of 80 cases over a 10-year period.
Clinical Research

Clinical Research

Journal of Clinical Case Reports

Author(s): Wong WM, Wong BC, Hui CK, Ng M, Lai KC,

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Abstract BACKGROUND: A total of 80 patients with pyogenic liver abscess managed at a single institution over a 10-year period were studied. METHODS: The clinical features, laboratory, imaging, and microbiologic findings, management strategy, and final outcome were studied. RESULTS: Fever and chills, leucocytosis and elevated alkaline phosphatase were the most common clinical and laboratory findings. Forty-one percent of patients were diabetic and 61\% had biliary pathology. Systemic antibiotics and image-guided aspiration had a success rate of 94\%. By multiple logistic regression analysis, malignancy on presentation (P = 0.011) was an independent risk factor associated with mortality. A past history of endoscopic sphincterotomy was an independent factor associated with resolution of liver abscess within 6 weeks (P = 0.03). CONCLUSION: Pyrexia, leucocytosis, elevated alkaline phosphatase, presence of diabetes, and underlying biliary pathology are common clinical and laboratory findings in patients with pyogenic liver abscess. Malignancy was associated with a poor outcome. Previous endoscopic sphincterotomy was a good prognostic factor for early resolution. Copyright 2002 Blackwell Publishing Asia Pty Ltd
This article was published in J Gastroenterol Hepatol and referenced in Journal of Clinical Case Reports

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