alexa Quinine may trigger torsades de pointes during astemizole therapy.
Pharmaceutical Sciences

Pharmaceutical Sciences

Journal of Clinical & Experimental Pharmacology

Author(s): Martin ES, Rogalski K, Black JN

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Abstract Because of serious cardiovascular events, warnings against concomitant use of certain medications with the use of antihistamine (HismanalR have been published and added to product labeling. Quinine, the optical isomer to quinidine, is included in these warnings. We present the case of a patient with only mild electrolyte disturbances who experienced an episode of torsades de pointes after a single dose of quinine while taking astemizole.
This article was published in Pacing Clin Electrophysiol and referenced in Journal of Clinical & Experimental Pharmacology

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