alexa Rapid detection of carbapenemase-producing Enterobacteriaceae from blood cultures.


Journal of Antimicrobial Agents

Author(s): Dortet L, Brchard L, Poirel L, Nordmann P

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Abstract The biochemical-based Carba NP test has been evaluated to detect carbapenemase-producing Enterobacteriaceae (n = 193) directly from spiked blood cultures. It was able to rapidly detect KPC (n = 50), IMP (n = 27), VIM (n = 37), NDM (n = 33) and OXA-48-like producers (n = 46) with sensitivity and specificity of 97.9\% and 100\%, respectively. This cost-effective technique may be implemented in any microbiology laboratory and offers a reliable test for an early identification of carbapenemase-producing Enterobacteriaceae directly from blood culture that could be useful for the management of infected patients. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases. This article was published in Clin Microbiol Infect and referenced in Journal of Antimicrobial Agents

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