alexa Reaching the last one per cent: progress and challenges in global polio eradication.


Journal of Antivirals & Antiretrovirals

Author(s): Kew O

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Abstract Since its launch in 1988, the World Health Organization's Global Polio Eradication Initiative has reduced worldwide polio incidence by >99\%. The most dramatic progress was achieved up to the year 2000, the original eradication target date, but subsequent years have seen only limited progress in preventing the last 1\% of cases. Recent gains in India and Nigeria have been offset by continued endemicity in Pakistan and Afghanistan, and repeated reseeding of wild poliovirus into polio-free areas has led to large outbreaks and re-established transmission. Although wild poliovirus type 2 was eradicated in 1999 and wild poliovirus type 3 may be nearing eradication, the continued emergence of circulating vaccine-derived polioviruses, especially type 2, presents ongoing challenges to stopping all poliovirus transmission. Published by Elsevier B.V. This article was published in Curr Opin Virol and referenced in Journal of Antivirals & Antiretrovirals

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