alexa Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene.


Medicinal chemistry

Author(s): Speck SH, Chatila T, Flemington E

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Abstract The switch from latent infection to virus replication in Epstein-Barr virus (EBV)-infected B cells is initiated by expression of the viral BZLF1 gene. Recent studies have identified the key cellular transcription factors involved in regulating this switch in viral programs and the signal transduction pathways to which they respond. Understanding this switch may facilitate development of strategies to interfere with EBV infection. This article was published in Trends Microbiol and referenced in Medicinal chemistry

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