Author(s): Ghetie MA, Vitetta ES
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Abstract Immunotoxin (IT) research has been ongoing for 15 years. During the past 2 years, work has focused on several areas: on improvements and developments in first- and second-generation ITs; the preparation of new immunotoxin constructs with anti-tumor activity; novel animal models for preclinical evaluation of immunotoxins; and clinical trials, which are now entering Phase II or III in humans.
This article was published in Curr Opin Immunol
and referenced in Journal of Bioterrorism & Biodefense