Author(s): Henderson AL, Schmitt TC, Heinze TM, Cerniglia CE
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Abstract Intestinal microfloras from human, rat, mouse, and monkey fecal samples and 14 pure cultures of anaerobic bacteria representative of those found in the human gastrointestinal tract metabolized the triphenylmethane dye malachite green to leucomalachite green. The reduction of malachite green to the leuco derivative suggests that intestinal microflora could play an important role in the metabolic activation of the triphenylmethane dye to a potential carcinogen.
This article was published in Appl Environ Microbiol
and referenced in Journal of Cytology & Histology