alexa Regeneration of the lens as a phenomenon of cellular transdifferentiation: regulability of the differentiated state of the vertebrate pigment epithelial cell.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Proteomics & Bioinformatics

Author(s): Eguchi G, Itoh Y

Abstract Share this page

Abstract The transdifferentiation of pigment epithelial cells in vitro was reviewed on the basis of results in the classic studies of lens regeneration in the newt. It is now known that pigment epithelial cells of avian embryos and human foetuses as well as of the newt can readily transdifferentiate into lens cells, when dissociated and cultured in vitro. The evidence now permits us to postulate that the potential of the pigment epithelial cell population for transdifferentiation is strongly conserved in vertebrates in general. Several environmental conditions controlling the processes have been suggested, and we can now provide an in vitro experimental system which is particularly useful for analysis of the molecular basis of transdifferentiation of the pigment epithelial cell, and its role as the cellular basis of lens regeneration.
This article was published in Trans Ophthalmol Soc U K and referenced in Journal of Proteomics & Bioinformatics

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • 9th International Conference on Bioinformatics
    October 23-24, 2017 Paris, France
  • 9th International Conference and Expo on Proteomics
    October 23-25, 2017 Paris, France

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version