alexa Registered report: tumour vascularization via endothelial differentiation of glioblastoma stem-like cells.
Biochemistry

Biochemistry

Biochemistry & Physiology: Open Access

Author(s): Chroscinski D, Sampey D, Maherali N Reproducibil

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Abstract The Nature in 2010 (Ricci-Vitiani et al., 2010). The experiments that will be replicated are those reported in Figure 4B and Supplementary Figure 10B (Ricci-Vitiani et al., 2010), which demonstrate that glioblastoma stem-like cells can derive into endothelial cells, and can be selectively ablated to reduce tumor progression in vivo, and Supplementary Figures S10C and S10D (Ricci-Vitiani et al., 2010), which demonstrate that fully differentiated glioblastoma cells cannot form functionally relevant endothelium. The Reproducibility Project: Cancer Biology is a collaboration between the eLife.
This article was published in Elife and referenced in Biochemistry & Physiology: Open Access

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