Author(s): Ryan KM, Phillips AC, Vousden KH
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Abstract Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.
This article was published in Curr Opin Cell Biol
and referenced in Journal of Nephrology & Therapeutics