alexa Relation of increased hemoglobin A(1c) levels to severity of peripheral arterial disease in patients with diabetes mellitus.

Author(s): Aronow WS, Ahn C, Weiss MB, Babu S

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Abstract The association between hemoglobin A(1c) levels and the severity of peripheral arterial disease (PAD) was investigated in 224 patients with diabetes mellitus and PAD. The mean hemoglobin A(1c) levels were 9.1 +/- 2.1\% in patients with diabetes with ankle-brachial indexes (ABIs) <0.60 and 7.1 +/- 0.9\% in those with ABIs of 0.60 to 0.89 (p <0.0001). Hemoglobin A(1c) levels <6.5\% were present in 2 of 89 patients with diabetes (2\%) with ABIs <0.60 and in 24 of 135 (18\%) with ABIs of 0.60 to 0.89 (p = 0.0004). Hemoglobin A(1c) levels <7.0\% were present in 24 of 89 patients with diabetes (27\%) with ABIs <0.60 and in 63 of 135 (47\%) with ABIs of 0.60 to 0.89 (p = 0.003). Hemoglobin A(1c) levels <7.5\% were present in 30 of 89 patients with diabetes (34\%) with ABIs <0.60 and in 92 of 135 (68\%) with ABIs of 0.60 to 0.89 (p <0.0001). In conclusion, the higher the hemoglobin A(1c) levels in patients with diabetes with PAD, the higher the prevalence of severe PAD. This article was published in Am J Cardiol and referenced in

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