alexa Relationship of obesity distribution and peripheral arterial occlusive disease in elderly men


Angiology: Open Access

Author(s): Planas A

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OBJECTIVE: To examine the relationships between total body fatness and abdominal fat distribution with peripheral arterial disease.

DESIGN: Cross-sectional.

SUBJECTS: Population-based sample of 708 men aged 55-74.

MEASUREMENTS: Body mass index (BMI) to estimate total body fatness and waist-to-hip ratio for abdominal fat distribution; peripheral arterial disease defined by ankle/brachial index <0.9; cardiovascular risk factors.

RESULTS: Peripheral arterial disease was observed in 13.4% of subjects. BMI did not correlate with peripheral arterial disease, whereas an increased waist-to-hip ratio over 0.966 (median value) doubled the prevalence of arterial disease. After controlling for smoking, diabetes, hypertension, high-density lipoprotein cholesterol and triglycerides, increased waist-to-hip ratio was independently associated with peripheral arterial disease (odds ratio 1.68; 95% confidence interval 1.05-2.70).

CONCLUSION: Abdominal fat distribution, but not total body fatness, is associated with peripheral arterial occlusive disease, independently of concurrent cardiovascular risk factors.

This article was published in Int J Obes Relat Metab Disord and referenced in Angiology: Open Access

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