Author(s): Boers M, Croonen AM, Dijkmans BA, Breedveld FC, Eulderink F,
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Abstract Renal abnormalities in 132 necropsied patients with rheumatoid arthritis were studied. Clinical findings before death included extra-articular manifestations of the disease (86\% of patients), systemic vasculitis (6\%), and uraemia (23\%). Necropsy findings included nephrosclerosis (90\%), systemic vasculitis (14\%) with kidney involvement in 8\%, amyloidosis (11\%), membranous glomerulopathy (8\%), and focal glomerular disease (8\%). Association with clinical data suggests that both rheumatoid and non-rheumatoid disease may play a part in the cause of these abnormalities.
This article was published in Ann Rheum Dis
and referenced in Journal of Genetic Syndromes & Gene Therapy