Author(s): Caramelo C, Lpez de Mendoza D, Ros F, Corrales M, Urbano J, , Caramelo C, Lpez de Mendoza D, Ros F, Corrales M, Urbano J,
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Abstract Major complications derived from the use of cocaine have been described, alter nasal or intravenous administration of the drug. These complications are related to vascular spasm and secondary organ damage. We present the case of an intestinal cocaine packer--in slang, "mule"--, who suffered massive absorption of the drug, resulting n bowel, liver and renal ischemia. This situation, previously undescribe in the literature, ended in kidney rupture. An attempt of embolization, was unsatisfactory, and nephrectomy was finally required. The patient recovered uneventfully, with progressive renal functional improvement. This case, albeit quite exceptional, is illustrative of several of the renal actions of cocaine, and reveals the effects of absorption of cocaine at the intestinal level.
This article was published in Nefrologia
and referenced in Journal of Clinical & Experimental Dermatology Research