alexa [Resistance of mycobacterial tuberculosis complex to the main antibacillary agent in Yaounde, Cameroon].
Surgery

Surgery

Journal of Vascular Medicine & Surgery

Author(s): Bercion R, Kuaban C

Abstract Share this page

Abstract To evaluate the current prevalence of initial and acquired resistance to the main antituberculosis drugs in Yaounde, isolates of M. tuberculosis complex obtained from sputum cultures of 602 adult patients with pulmonary tuberculosis (516 new cases and 86 old cases) consecutively admitted into the tuberculosis centre of Hôpital JAMOT from July 1994 to December 1995 were studied. The susceptibility of isolates to the major antituberculosis drugs was tested by the indirect proportion method. The overall resistance rate (1 or more drugs) was 35.2\%, with initial resistance 31.8\% (164 of 516) and acquired resistance 55.8\% (48 of 86). Initial resistance to streptomycin was the most frequent (20.5\%), followed by isoniazid 12.4\%), thiacetazone (5.6\%), rifampicine (0.8\%) and ethambutol (0.4\%). Initial resistance was noted as 25\% to 1 drug, 5.8\% to 2 drugs, 0.8\% to 3 drugs and 0.2\% to 4 drugs. Acquired resistance to isoniazid was the most frequent (45.3\%), followed by streptomycin (40.7\%), rifampicine (30.2\%), thiacetazone (10.5\%) and ethambutol (9.3\%). Acquired resistance was found as 13.9\% to one drug, 19.8\% to 2 drugs, 12.8\% to 3 drugs and 9.3\% to 4 drugs. A combined resistance to rifampicine and isoniazid in the same patient was noted in 0.8\% of the new cases and in 26.7\% of the old cases. These high rates af antituberculosis drug resistance in Yaounde underline the urgent need to reestablish a tuberculosis control programme in Cameroon.
This article was published in Bull Soc Pathol Exot and referenced in Journal of Vascular Medicine & Surgery

Relevant Expert PPTs

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords