alexa Respiratory viruses in the pediatric intensive care unit: prevalence and clinical aspects.


Pediatrics & Therapeutics

Author(s): Straliotto SM, Siqueira MM, Machado V, Maia TM

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Abstract A survey was conducted in two pediatric intensive care units in hospitals in Porto Alegre, Brazil, in order to monitor the main respiratory viruses present in bronchiolitis and/or pneumonia and their involvement in the severity of viral respiratory infections. Viral respiratory infection prevalence was 38.7\%. In bronchiolitis, respiratory syncytial virus (RSV) was detected in 36\% of the cases. In pneumonia, the prevalence rates were similar for adenovirus (10.3\%) and RSV (7.7\%). There was a difference among the viruses detected in terms of frequency of clinical findings indicating greater severity. Frequency of crackles in patients with RSV (47.3\%) showed a borderline significance (p = 0.055, Fisher's exact test) as compared to those with adenovirus (87.5\%). The overall case fatality rate in this study was 2.7\%, and adenovirus showed a significantly higher case fatality rate (25\%) than RSV (2.8\%) (p = 0.005). Injected antibiotics were used in 49\% of the children with RSV and 60\% of those with adenovirus. Adenovirus was not detected in any of the 33 children submitted to oxygen therapy. This article was published in Mem Inst Oswaldo Cruz and referenced in Pediatrics & Therapeutics

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