alexa Retinoic acid fails to induce differentiation in human teratocarcinoma cell lines that express high levels of a cellular receptor protein
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Stem Cell Research & Therapy

Author(s): Peter W Andrews, Klaus I Matthaei, David L Bronson

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Human embryonal carcinoma (EC) cells and other human teratocarcinoma-derived cells lines were not observed to differentiate in culture in response to retinoic acid. Nevertheless, they express high levels of a cellular binding protein (cRABP) which, in murine EC cells, appears to be necessary for the induction of differentiation by retinoic acid.

This article was published in Exp Cell Res and referenced in Journal of Stem Cell Research & Therapy

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