alexa Review of the literature and a recommended system of malignancy grading in oral squamous cell carcinomas.
Oncology

Oncology

Journal of Cancer Science & Therapy

Author(s): Anneroth G, Batsakis J, Luna M

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Abstract A review of histologic classification systems for grading of malignancy in squamous cell carcinomas of the head and neck region is presented. Reasons behind the varying results obtained in studies using histomorphologic grading schemes are presented and potential errors involved in this type of clinical research are discussed. Requirements for the study of correlations between malignancy grade scoring, and recurrence and survival rates are presented. These include factors as patient selection, clinical staging, and follow-up principles. Special attention must be given to treatment modalities, establishment of negative surgical margins and occurrence of regional lymph node and/or distant metastases.
This article was published in Scand J Dent Res and referenced in Journal of Cancer Science & Therapy

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