Author(s): Herring R, Caldwell G, Wade S
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Abstract A case of severe rhabdomyolysis caused by an interaction between fusidic acid and simvastatin is described. Fusidic acid significantly reduces the excretion of simvastatin resulting in increased plasma levels thereby increasing the side effect profile. Simvastatin treatment should be temporarily withheld during treatment with fusidic acid.
This article was published in BMJ Case Rep
and referenced in Journal of Clinical & Experimental Pharmacology