alexa Right liver lobe albumin ratio: contribution to non-invasive assessment of portal hypertension.


Journal of Liver

Author(s): Alempijevic T, Bulat V, Djuranovic S, Kovacevic N, Jesic R,

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Abstract AIM: To study the value of biochemical and ultraso-nographic parameters in prediction of presence and size of esophageal varices. METHODS: The study includes selected cirrhotic patients who underwent a complete biochemical workup, upper digestive endoscopic and ultrasonographic examinations. Albumin/right liver lobe diameter and platelet count/spleen diameter ratios were calculated. The correlation between calculated ratio and the presence and degree of esophageal varices was evaluated. RESULTS: Ninety-four subjects (62 males, 32 females), with a mean age of 52.32 +/- 13.60 years, were studied. Child-Pugh class A accounted for 42.6\%, class B 37.2\%, whereas class C 20.2\%. Esophageal varices (OE) were not demonstrated by upper digestive endoscopy in 24.5\%, while OE grade I was found in 22.3\% patients, grade II in 33.0\%, grade III in 16.0\%, and grade IV in 4.3\%. The mean value of right liver lobe diameter/albumin ratio was 5.51 +/- 1.82 (range from 2.76 to 11.44), while the mean platelet count/spleen diameter ratio was 1017.75 +/- 729.36 (range from 117.39 to 3362.50), respectively. Statistically significant correlation was proved by Spearman's test between OE grade and calculated ratios. The P values were 0.481 and -0.686, respectively. CONCLUSION: The right liver lobe diameter/albumin and platelet count/spleen diameter ratios are non-invasive parameters providing accurate information pertinent to determination of presence of esophageal varices, and their grading in patients with liver cirrhosis.
This article was published in World J Gastroenterol and referenced in Journal of Liver

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