alexa Risk of autism associated with general anesthesia during cesarean delivery: a population-based birth-cohort analysis
Reproductive Medicine

Reproductive Medicine

Clinics in Mother and Child Health

Author(s): Chien LN, Lin HC, Shao YH, Chiou ST, Chiou HY

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The rates of Cesarean delivery (C-section) have risen to >30% in numerous countries. Increased risk of autism has been shown in neonates delivered by C-section. This study examined the incidence of autism in neonates delivered vaginally, by C-section with regional anesthesia (RA), and by C-section with general anesthesia (GA) to evaluate the risk of autism associated with C-section and obstetric anesthesia. During a mean follow-up of 4.3 years, the incidence of autism was higher in neonates delivered by C-section with GA than in neonates delivered vaginally, with an adjusted risk of 1.52 (95% confidence interval 1.18-1.94). However, the adjusted risk of autism in neonates delivered by C-section with RA and in neonates delivered vaginally was nonsignificantly different.

This article was published in J Autism Dev Disord and referenced in Clinics in Mother and Child Health

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