alexa Risk of postoperative bleeding after dental procedures in patients on warfarin: a retrospective study.


Journal of Blood Disorders & Transfusion

Author(s): Hong C, Napenas JJ, Brennan M, Furney S, Lockhart P

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Abstract OBJECTIVES: The purpose of this retrospective study was to investigate the frequency of bleeding complications after invasive dental procedures in warfarinized patients and the possible risk factors. STUDY DESIGN: The CoaguChek System was used to obtain an in-office international normalized ratio (INR) value for 122 patients (240 appointments), of which the mean age was 57.0 ± 15.9 years and 50\% were males. Demographic and clinical information were obtained retrospectively from dental and medical records. RESULTS: Five episodes (mean INR: 2.0 ± 0.8) of persistent bleeding were identified; 4 were after extractions and 1 was after implant placement. The frequency of bleeding was 4.8\%, if only considering surgical procedures. Postoperative bleeding was significantly higher (P < .05) in patients who were taking anti-thrombotic medications in addition to warfarin. CONCLUSIONS: There is a low incidence of persistent bleeding after invasive dental procedures in warfarinized patients but the risk appears to increase with the use of concomitant anti-thrombotic medications. Copyright © 2012 Elsevier Inc. All rights reserved. This article was published in Oral Surg Oral Med Oral Pathol Oral Radiol and referenced in Journal of Blood Disorders & Transfusion

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