alexa Role for proteases and HLA-G in the pathogenicity of influenza A viruses.


Journal of Antivirals & Antiretrovirals

Author(s): Foucault ML, Moules V, RosaCalatrava M, Riteau B

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Abstract Influenza is one of the most common infectious diseases in humans occurring as seasonal epidemic and sporadic pandemic outbreaks. The ongoing infections of humans with avian H5N1 influenza A viruses (IAV) and the past 2009 pandemic caused by the quadruple human/avian/swine reassortant (H1N1) virus highlights the permanent threat caused by these viruses. This review aims to describe the interaction between the virus and the host, with a particular focus on the role of proteases and HLA-G in the pathogenicity of influenza viruses. Copyright © 2011 Elsevier B.V. All rights reserved. This article was published in J Clin Virol and referenced in Journal of Antivirals & Antiretrovirals

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