Author(s): Sinuani I, Beberashvili I, Averbukh Z, Sandbank J
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Abstract Interleukin-10 (IL-10), a cytokine with anti-inflammatory and immunomodulatory functions, regulates the biology of B and T cells. The present review describes the role of IL-10 in normal renal physiology, during acute kidney injury and in the development of chronic renal failure. We further discuss IL-10-induced cellular and molecular pathways and their link to the progression of kidney injury.
This article was published in World J Transplant
and referenced in Journal of Molecular and Genetic Medicine