Author(s): Lin EY, Pollard JW
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Abstract Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis.
This article was published in Br J Cancer
and referenced in Journal of Carcinogenesis & Mutagenesis