Author(s): Sun X, Sit A, Feinberg MW
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Abstract The microRNA family, miR-181, plays diverse roles in regulating key aspects of cellular growth, development, and activation. Accumulating evidence supports a central role for the miR-181 family in vascular inflammation by controlling critical signaling pathways, such as downstream NF-κB signaling, and targets relevant to endothelial cell activation and immune cell homeostasis. This review examines the current knowledge of the miR-181 family's role in key cell types that critically control cardiovascular inflammation under pathological and physiological stimuli. © 2013 Published by Elsevier Inc.
This article was published in Trends Cardiovasc Med
and referenced in Journal of Stem Cell Research & Therapy